MNDA

Size

£655.00

SKU:: 590605
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 13aa near the C-terminal of human MNDA, located within the 50aa of MNDA. Species sequence homology: gorilla (100%), chimpanzee (100%), monkey (92%)
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:: MNDA controls the expression of MCL-1 and BCL02 in chronic lymphocytic leukemia cells. MNDA is also a useful marker in the recognition and differential diagnosis of marginal zone lymphomas. MNDA has a role in regulating programmed cell death in myeloid progenitor cells, and its down-regulation in myelodysplastic syndromes is related to granulocyte-macrophage progenitor cell sensitivity to TRAIL-induced programmed cell death. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: 2ug/ml Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.