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590096

CD51 (Not for Export EU)

Size

£717.00

SKU:
590096
Purity:
Serum
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to aa1021-1034 of human CD51 (alpha V integrin) at C-terminal.
Format:
Supplied as a liquid, 0.05% sodium azide.
Extra Details:
CD51 (integrin alpha V subunit) associates with CD61 (integrin beta 3 subunit) binding to the RGD sequence in extracellular matrix proteins like vitronectin, fibrinogen, thrombospondin, von Willebrand factor and osteopontin. The alphaV/beta3 heterodimer is expressed in endothelial cells, leukocytes, NK cells, macrophages, neutrophils, platelets and several malignant tumor cells and seems to play a role in embryo implantation, angiogenesis, wound healing and cancer. alpha V/beta 3  is also highly expressed in osteoclasts being important for bone resorption. Applications: Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:5000 Immunohistochemistry (frozen/paraffin): 1:500 Immunocytochemistry: 1:1000 Immunoprecipitation: 5ul per 5x10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice