Anthrax Lethal Factor (LF, ALF)

Size

£678.00

SKU:: 589955
Purity:: Purified by Protein G affinity chromatography from hybridoma tissue culture supernatant..
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Anthrax lethal factor.
Clone:: LF2
Format:: Supplied as a liquid in PBS, 0.01% sodium azide.
Extra Details:: Anthrax lethal factor (LF) is a zinc-dependent protease that cleaves mitogen-activated protein kinase kinase (MAPKK) and causes lysis of macrophages. LF, together with protective antigen, forms lethal toxin, which is the dominant virulence factor produced by B. anthracis and is the major cause of death in infected animals. Lethal toxin has been reported to trigger apoptosis in human melanoma cells. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.