TNF alpha, Infliximab Biosimilar

Size

£479.00

SKU:: 587272
Purity:: ≥95% by reducing SDS-PAGE, HPLC. Endotoxin: ≤1EU/mg (LAL).
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Human
Immunogen:: Recombinant human TNF alpha, expressed in CHO cells.
Format:: Supplied as a 0.2uM filtered solution, pH 7.2. No stabilizers or preservatives added.
Extra Details:: Infliximab, a chimeric anti-TNF-alpha monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-alpha from binding to its receptor in the cell. Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNF alpha) plays important roles in the regulation of autoimmune reaction. Applications: Suitable for use in ELISA, Neutralization, Functional Assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.