587135
IgG1 Isotype Control, In Vivo Grade Recombinant Mouse
Size
£475.00
- SKU:
- 587135
- Purity:
- ≥95% by reducing SDS-PAGE
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Immunogen:
- Recombinant mouse IgG1.
- Clone:
- 12B9
- Format:
- Supplied as a 0.2uM filtered solution. No stabilizers or preservatives added.
- Extra Details:
- Mouse IgG1 isotype control and mutants (natural and engineered mIgG1 isotype controls) are useful for in vitro and in vivo studies from ELISA, Western blot (WB), to cell-based assay to animal model study. The isotypes of mouse IgG antibody reagents used in scientific research and clinical diagnostics are mainly mouse IgG1 kappa. Mouse IgG1 antibodies and engineered mutants are also used in therapeutic drug discovery. Mouse IgG1 antibodies are more like human IgG4 antibodies than human IgG1 antibodies, which behave more like mouse IgG2a or IgG2c antibodies. Many antibody drugs especially those targetting immune checkpoint proteins use the human IgG4 constant regions. Applications: Suitable for use in ELISA, Western Blot, Flow Cytometry, Immunoprecipitation, Immunohistochemistry and in vivo animal model research. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen/paraffin Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice