586946
Interleukin-13 receptor subunit alpha-1, Active, Recombinant, Human, His-Tag, aa22-343 (IL13RA1)
Size
£384.00
- SKU:
- 586946
- Molecular Weight:
- 37.7
- Purity:
- ≥95% (SDS-PAGE) Endotoxin: ≤1EU/ug (LAL)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with sterile ddH2O to 0.1-1mg/ml.
- Extra Details:
- Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. Partial recombinant protein corresponding to aa22-343 from human Interleukin 13 receptor subunit alpha, fused to 6xHis-Tag at C-terminal, expressed in Mammalian cells. Molecular Weight: ~37.7kD Biological Activity: The ED50 as determined by its ability to inhibit IL-13-dependent proliferation of TF-1 human erythroleukemic cells is less than 30ng/ml. Amino Acid Sequence: GGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNST Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice