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586908

Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, Active, Recombinant, Human, His-Tag, aa23-320 (CSF2RA)

Size

£351.00

SKU:
586908
Molecular Weight:
35.5
Purity:
≥95% (SDS-PAGE) Endotoxin: ≤1EU/ug (LAL)
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
Supplied as a lyophilized powder from 20mM PBS, pH 7.4. Reconstitute with sterile ddH2O, to a concentration of 0.1-1mg/ml.
Extra Details:
Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Partial Recombinant protein corresponding to aa23-320 from human Granulocyte-macrophage colony-stimulating factor receptor subunit alpha fused to 6X His-Tag at C-terminal, expressed in mammalian cell. Molecular Weight: ~35.5kD Biological Activity: The ED50 as determined by its ability to inhibit GM-CSF-dependent proliferation of TF?1 human erythroleukemic cells is less than 5ng/ml. Amino Acid Sequence: EKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDG Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice