Thyroglobulin

Size

£1,011.00

SKU:: 553898
Purity:: Purified by Protein A affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Clone:: 56.7D7
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Thyroglobulin is a ~660kD homodimer produced by the thyroid gland, specifically in the thyrocytes, and stored within the follicular lumen. Thyroglobulin is the precursor of the iodated thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones affect protein, fat and carbohydrate metabolism. Defects in thyroglobulin production can lead to goiter, and increased susceptibility to autoimmune thyroid type 3 diseases, such as Graves disease and Hashimoto thyroiditis. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:10,000-1:100,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.