Rac1,2,3

Size

£518.00

SKU:: 552221
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-189 from human Rac1,2,3, expressed in E. coli.
Clone:: AT2G10
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: Rac is a subfamily of the Rho family of GTPases, small (~21kD) signaling G proteins (more specifically a GTPase). When bound to GTP, Rac is activated. In its activated state, Rac participates in the regulation of cell movement, through its involvement in structural changes to the actin Cytoskeleton. Rac is small GTPases that have been linked to multiple human cancers and are implicated in epithelial to mesenchymal transition, cellcycle progression,migration/invasion, tumor growth, angiogenesis, and oncogenic transformation. Applications: Suitable for use in ELISA, Western Blot and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.