PD-1 (CD279), Recombinant, Human, aa25–167, Fc-Tag

Size

£887.00

SKU:: 544342
Molecular Weight:: 42.6
Purity:: ≥90%
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 20% glycerol. Labeled with Biotin.
Extra Details:: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors. Source: Recombinant protein corresponding to aa25–167 from human PD-1, fused at the C-terminus to the Fc portion of human IgG1, expressed in HEK293 cells. Molecular Weight: ~42.6kD Assay Conditions: PD-1-PD-L1 binding activity, measured using the using the PD-1:PDL1 [Biotinylated] Inhibitor Screening BioAssay™ Kit. Applications: Suitable for use in the study of protein-protein interaction and in vitro and in vivo protein function. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.