Ross River Virus E2 Glycoprotein

Size

£672.00

SKU:: 544061
Application:: Flow Cytometry
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Clone:: D7 (recomb)
Format:: Supplied as a liquid in PBS, 0.02% Proclin 300
Extra Details:: Recombinant monoclonal antibody to Ross River virus E2 Glycoprotein with variable domain sequences of the original mouse IgG format, for improved compatibility with existing reagents, assays and techniques.. Manufactured using a proprietary recombinant platform technology. Ross River fever (RRF), also known as epidemic polyarthritis, is an illness caused by infection with the Ross River virus, which is related to another mosquito-borne virus, Barmah Forest virus (BFV). The virus was first isolated in 1959 from a mosquito trapped along the Ross River in Townsville, Queensland. Since then, outbreaks have occurred in all Australian states, including Tasmania, and metropolitan areas. RRV and BFV are the two most common mosquito-borne viruses in Western Australia. RRV infection cannot be spread from human to human. It is spread from animals to humans by a number of different types of mosquitoes with Culex annulirostris, Aedes vigilax (salt marsh mosquito) and Aedes notoscriptus being most common. Aedes vigilax breeds in salty pools in mangroves and salt marshes after flooding by spring tides and heavy rains. Culex annulirostris breeds in permanent bodies of fresh water while Aedes notoscriptus breeds in containers close to homes and other human activity. People suffering from RRV or BFV diseases may experience a wide range of symptoms common to both viruses. Symptoms and their severity vary from person to person but can include painful and/or swollen joints (the most commonly affected joints are the wrists, knees, ankles, fingers, elbows, shoulders and jaw). Pain usually develops quickly and may be intense and more severe in different joints at different times. Joint pain is much more common than swelling. Other symptoms include sore muscles, aching tendons, skin rashes (although these tend to be more common to BFV disease), fever, tiredness, headaches and swollen lymph nodes. Fever, nausea and skin rashes usually disappear within the first 2 weeks of illness. Joint, muscle and tendon pain may last much longer, upto 3 months. In rare cases, symptoms can persist or recur for up to a year or more. BFV symptoms may not last as long as those for RRV Applications: Suitable for use in Flow Cytometry. It can also be used to detect RRV binding to cells. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice