Mumps Virus Nucleoprotein

Size

£704.00

SKU:: 544053
Purity:: Purified by Protein A affinity chromatography from ascites fluid or culture medium.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Clone:: 6008
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: Mumps virus infection typically causes swelling of the parotid salivary glands (parotitis) and may lead to serious complications such as meningitis, orchitis, and hearing loss. Symptoms are often more severe in adults than in children. Routine Measles Mumps Rubella (MMR) vaccination has greatly reduced the incidence of Mumps although sporadic Mumps outbreaks have occurred among vaccinated populations in the United States and globally (Latner, 2017). Mumps is caused by a negative-sense single-stranded RNA paramyxovirus which is transmitted by respiratory droplets or direct contact with an infected person. Humans are the only natural host for the virus. Virions are enveloped and contain fusion and attachment proteins on the virion surface. The nucleoprotein of the Mumps virus, also known as a nucleocapsid, is the basic architecture of the virus, comprised of a core of nucleic acid captured in a protein coat. Laboratory diagnosis of Mumps is currently based on isolation of virus, detection of viral nucleic acid, or serological confirmation of IgM Mumps antibodies. Applications: Suitable for use in ELISA and Immunofluorescence. Other applications not tested. Recommended Dilution: ELISA: 1:20-1:200 Immunofluoscence: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice