Nrf2

Size

£488.00

SKU:: 539881
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa530-610 of human Nrf2 at C-terminal.
Format:: Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Extra Details:: NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for NFE2L2. Applications: Suitable for use in Western Blot, Immunofluorescence, Immunohistochemistry, and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:2000 Immunofluorescence: 1:200-1:1000 Immunohistochemistry (paraffin): 1:100-1:300 ELISA: 1:40,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.