516656
CD3 epsilon
Size
£840.00
- SKU:
- 516656
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Human peripheral E+ cells.
- Clone:
- OKT-3 (muromonab) (recomb)
- Format:
- Supplied as a liquid in PBS, 0.02% Proclin 300.
- Extra Details:
- Recombinant monoclonal antibody to CD3 epsilon. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the hybridoma OKT-3 (muromonab). CD3 is closely associated on the lymphocyte cell surface with the T cell antigen receptor TcR (2-4). It is believed that the CD3 complex transmits activational signals to the T cell’s interior upon antigen recognition by TcR. CD45 (LCA), a protein tyrosine phosphatase, is a potent regulator of signal transduction by the CD3 complex. It reacts with the majority of peripheral blood T lymphocytes, a major proportion of thymocytes, the majority of T cell chronic lymphocytic leukemia cells, Sézary leukemias and approximately 70% of acute lymphoblastic leukemias of T cell origin. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice