Chlamydia LPS

Size

£639.00

SKU:: 516572
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Clone:: 1646
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: Members of the genus Chlamydia are obligate intracellular gram-negative bacteria that belong to the family Chlamydiaceae. Three species of Chlamydia are known to be pathogenic to humans including Chlamydia trachomatis (C.trachomatis), Chlamydia pneumonia (C.pneumonia) and Chlamydia psittaci (C.psittaci). Chlamydia trachomatis strains are divided into three biovars, which are further divided into fifteen serovars A, B, Ba, serovars C-K and serovars L1-L3. Chlamydia trachomatis serovars A-C cause eye infections known as trachoma. Serovars D-K are responsible for bacterial sexually transmitted genital tract infections in women and men. Chlamydia trachomatis serovars L1, L2 and L3 are responsible for a condition known as Lymphogranuloma venereum (LGV) (Elwell, C). In women, C.trachomatis infects the cervix which may lead to cervicitis. However, 70-80% of women with C.trachomatis genital tract infection remain asymptomatic. In 10% of cases, the bacterium can infect the upper genital tract leading to pelvic inflammatory disease, scarring of the Fallopian tubes, ectopic pregnancies and infertility. C.trachomatis can also be transmitted to babies born to infected untreated mothers during childbirth, causing conjunctivitis or pneumonia. C.pneumonia infects the lungs causing a type of atypical pneumonia. The bacteria can be spread via airborne droplets from person to person and through close contact with infected individuals. Primary infection typically occurs in children, but re-infection can occur later in adult life (CDC). C.psittaci infection primarily affects birds such as parrots, parakeets, doves and pigeons causing the disease psittacosis. C.psittaci can be transmitted to humans that come into close contact with birds through exposure to bird feces and inhalation of respiratory particles from infected birds. In humans, C.psittaci infection causes an acute respiratory disease with flu-like symptoms (GOV.UK). Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:20-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice