Erythropoietin, Recombinant, Mouse, aa27-192, His-Tag

Size

£342.00

SKU:: 497035
Molecular Weight:: 19.8176
Purity:: ≥95% (SDS-PAGE). Endotoxin: ≤1EU/1ug (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Extra Details:: EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related tot hrombopoietin. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types. Recombinant protein corresponding to aa27-192 from mouse Erythropoietin, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~19.8kD Biological Activity: Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤2ng/ml. Amino Acid Sequence: <ADP>MAPPRLI CDSRVLERYI LEAKEAENVT MGCAEGPRLS ENITVPDTKV NFYAWKRMEV EEQAIEVWQG LSLLSEAILQ AQALLANSSQ PPETLQLHID KAISGLRSLT SLLRVLGAQK ELMSPPDTTP PAPLRTLTVD TFCKLFRVYA NFLRGKLKLY TGEVCRRGDR <HHHHHH> Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice