470179
TFPI (EPI, LACI, TFI, TFPI1)
Size
£685.00
- SKU:
- 470179
- Application:
- WB
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Protein corresponding to aa1-304 from full length human TFPI
- Format:
- Supplied as a liquid in PBS, pH 7.4
- Extra Details:
- This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq] Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTII TDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTR QCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIK TTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCER FKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYG TQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGL CRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQ ECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIF VKNM Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice