470156
SF3B2 (SAP145, SF3B145, SF3b1, SF3b150)
Size
£685.00
- SKU:
- 470156
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Protein corresponding to aa1-636 from full length human SF3B2.
- Format:
- Supplied as a liquid in PBS, pH 7.4
- Extra Details:
- This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq] Applications: Suitable for use in Immunofluorescence, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEM ETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKK KKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIE YVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKL DKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEA PKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQ DPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKP PFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKV RPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGK EFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPW LIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGW GKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTP WGELEPSDEESSEEEEEEESDEDKPDETGFITPADSG LITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQL FTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPE LQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVE KEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKE FKF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice