NCF2 (FLJ93058, NCF-2, NOXA2, P67-PHOX, P67PHOX)

Size

£685.00

SKU:: 470080
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Protein corresponding to aa1-526 from full length human NCF2.
Format:: Supplied as a liquid in PBS, pH 7.4.
Extra Details:: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein. [provided by RefSeq] Applications: Suitable for use in Immunofluorescence, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHS RICFNIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQ RGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQ FKLFACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSE PRHSKIDKAMECVWKQKLYEPVVIPVGRLFRPNERQV AQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEP PPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPG NIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI HPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQ KEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQ VRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMK DAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADA NNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIIL VLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLEST RREV Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice