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469900

ANGPTL3 (ANGPT5)

Size

£685.00

SKU:
469900
Application:
WB
Purity:
Purified
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Protein corresponding to aa1-460 from full length human ANGPT3
Format:
Supplied as a liquid in PBS, pH 7.4.
Extra Details:
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq] Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAML DDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFD QSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMS LELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETP EHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQH SQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNE IRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFH VYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGR LDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEY SFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFSTWD HKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNK PRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDS ESFE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice