β-Nicotinamide-d4 Mononucleotide (d4-major)

Size

£614.00

SKU:: 469744
Molecular Weight:: 338.24
Purity:: ≥95%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1094-61-7
Format:: White to off-white solid
Extra Details:: β-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. Synonyms: 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-d4 Inner Salt CAS No: 1094-61-7 unlabeled Molecular Formula: C₁₁H₁₁D₄N₂O₈P Molecular Weight: 338.24 Appearance: White to off-white solid Purity: ≥95% Melting Point: >113°C (dec.) Solubility: Methanol (Slightly), Water (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.