β-Hydroxyisovaleric Acid-d8

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£479.00

SKU:: 469713
Molecular Weight:: 126.18
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 123743-99-7
Extra Details:: β-Hydroxyisovaleric Acid-d8 is the isotope labeled analog of β-Hydroxyisovaleric Acid; a metabolite of the essential amino acid Leucine. It is synthesized in the human body and studies suggest that β-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated β-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency. Synonyms: 3-Hydroxy-3-methylbutanoic Acid-d8; 3-Hydroxy-3-methylbutyric Acid-d8; 3-Hydroxyisovaleric Acid-d8; β-Hydroxy-β-methylbutyric Acid-d8 CAS No: 123743-99-7 Unlabeled: 625-08-1 Molecular Formula: C₅H₂D₈O₃ Molecular Weight: 126.18 Purity: ≥97% (Isotopic) Appearance: Colorless to yellow oil Solubility: DMSO (Sparingly), Methanol (Slightly) Method for Determining Identity: H NMR and C NMR Spectrometric Analysis and Mass Spectrometric Analysis TLC Conditions: SiO2; Dichloromethane: Methanol: Acetic Acid=8:1:0.1; Visualized with AMCS; Single Spot, Rf=0.65 Normalized Intensity: d0=0.00%, d1=0.00%, d2=0.01%, d3=0.03%, d4=0.00%, d5=0.07%, d6=0.31%, d7=4.48%, d8=95.10% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4ºC for 6 months after time of receipt.