466557
Substance P
Size
£320.00
- SKU:
- 466557
- Molecular Weight:
- 1347.63
- Purity:
- ≥96% (HPLC)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 33507-63-0
- Format:
- White powder trifluoroacetate salt
- Extra Details:
- Substance P is a neurokinin undecapeptide neurotransmitter and neuromodulator. Neuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goα, Gq/11α, and Gsα subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils. Sequence: H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂ CAS No: 33507-63-0 Molecular Formula: C₆₃H₉₈N₁₈O₁₃S Molecular Weight: 1347.63 Solubility: DMSO; Water; 5% acetic acid, 1mg/ml Appearance: White powder trifluoroacetate salt Purity: ≥96% (HPLC) Storage and Stability: Store at -20°C. Hygroscopic under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient