466066
Shield 1

Size
£607.00
- SKU:
- 466066
- Molecular Weight:
- 748.9
- Purity:
- ≥99%
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 914805-33-7
- Format:
- White to off-white solid
- Extra Details:
- Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein. Synonyms: 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-,(1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-(4-morpholinyl)ethoxy]phenyl]propyl ester, (2S)-2-Piperidinecarboxylic Acid Molecular Formula: C42H56N2O10 Molecular Weight: 748.9 Appearance: White to off-white solid Purity: ≥99% Solubility: Chloroform (Slightly), Methanol (Slightly) Method for Determining Ientity: Proton NMR Spectroscopic and Mass Spectrometric analysis TLC Conditions: SiO2; Dichloromethane:Methanol=9:1; Visualized with UV and KMnO4; Single Spot, Rf=0.75 Elemental Analysis: Calculated: %C: 67.36, %H: 7.54, %N: 3.74 Specific Rotation (c=0.2, Methanol): As Reported Storage and Stability: Store at 4°C. Hygroscopic; Store under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient
