464725
Rimacalib
Size
£1,055.00
- SKU:
- 464725
- Molecular Weight:
- 394.44
- Purity:
- ≥99%
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 215174-50-8
- Format:
- Supplied as a off-white to pale orange solid
- Extra Details:
- Rimacalib, a inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib. The IC50s of Rimacalib are ~1uM for CaMKIIα to ~30uM for CaMKIIγ. Synonyms: SMP 114; N-[3-[(1S)-1-(2-Fluoro[1,1'-biphenyl]-4-yl)ethyl]-5-isoxazolyl]-4-morpholinecarboximidamide CAS No: 215174-50-8 HCl Salt: 215174-78-0 Molecular Formula: C₂₂H₂₃FN₄O₂ Molecular Weight: 394.44 Appearance: Supplied as a off-white to pale orange solid Purity: ≥99% Melting Point: >56°C (dec.) Solubility: Chloroform (Slightly), Methanol (Slightly), DMSO (125mg/ml) Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient