Regorafenib (Pyridine)-N-oxide

Size

£422.00

SKU:: 464563
Molecular Weight:: 498.81
Purity:: As reported
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 835621-11-9
Format:: White to off-white solid
Extra Details:: Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib and is used for treatment and prevention of cancer. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5nM, respectively. Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 1-Oxide CAS No: 835621-11-9 Molecular Formula: C₂₁H₁₅ClF₄N₄O₄ Molecular Weight: 498.81 Appearance: White to off-white solid Purity: As reported Melting Point: 223-227°C Solubility: DMSO (Slightly), Methanol (Slightly, Heated) Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.