(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

Size

£422.00

SKU:: 463679
Molecular Weight:: 209.29
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 180272-45-1
Format:: Supplied as a Off-White to Pale Beige Solid
Extra Details:: (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin (S676700), an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists. Molecular Formula: C15H15N Solubility: Dichloromethane (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) Molecular Weight: 209.29 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.