462343
PHA 767491
Size
£282.00
- SKU:
- 462343
- Molecular Weight:
- 213.24
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 845714-00-3
- Extra Details:
- PHA 767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. It blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites. Inhibits cell proliferation in a variety of human cell lines and induces apoptosis in a p53-independent manner in vivo. Also inhibits mitogen-activated protein kinase-activated protein kinase-2 (MK-2). Molecular Formula: C12H11N3O Molecular Weight: 213.24 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient