Octyl-α-hydroxyglutarate

Size

£288.00

SKU:: 461489
Molecular Weight:: 260.33
Storage Conditions:: -20°C
Supplier:: United States Biological
Extra Details:: Octyl-α-hydroxyglutarate is a cell-permeable derivative of 2-HG (α-hydroxyglutaric acid). Mutations in isocitrate dehydrogenase 1 (IDH1 and IDH2) associated with certain cancers cause isocitrate to metabolize into 2-HG as opposed α-ketoglutarate, inhibiting α-ketoglutarate-dependant dioxygenases including lysine demethylases and DNA hydroxylases. This compound is suitable for IDH (isocitrate dehydrogenase) related research. Molecular Formula: C13H24O5 Molecular Weight: 260.33 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.