457591
N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester
Size
£685.00
- SKU:
- 457591
- Molecular Weight:
- 413.37
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 1874196-88-9
- Format:
- Supplied as a Pale Yellow Oil
- Extra Details:
- N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester is an intermediate in synthesizing PSI-7977-D5 (P839643), an isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Molecular Formula: C18H16D5N2O7P Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol Molecular Weight: 413.37 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient