L-Methionine [R,S]-Sulfoximine-13C5

Size

£544.00

SKU:: 453374
Molecular Weight:: 185.19
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a White Solid
Extra Details:: L-Methionine [R,S]-Sulfoximine-13C5,15N is the isotope labelled analog of L-Methionine [R,S]-Sulfoximine. Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM). Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. Molecular Formula: 13C5H12N2O3S Solubility: Water (Slightly) Molecular Weight: 185.19 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.