453063
KPT 330
Size
£364.00
- SKU:
- 453063
- Molecular Weight:
- 443.31
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 1393477-72-9
- Extra Details:
- Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO1/CRM1 Inhibitor. Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia. Selinexor potentiates the antitumor activity of gemcitabine in human pancreatic cancer through inhibition of tumor growth, depletion of the antiapoptotic proteins, and induction of apoptosis. Selinexor has strong activity against primary AML cells while sparing normal stem and progenitor cells. Synonyms: Selinexor; Xpovio; (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide CAS No: 1393477-72-9 Molecular Formula: C17H11F6N7O Molecular Weight: 443.31 Purity: ≥98% Appearance: White to off-white solid Solubility: DMSO Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient