Isonicotinic Acid Vanillylidenehydrazide

Size

£320.00

SKU:: 452612
Molecular Weight:: 271.27
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 149-17-7
Extra Details:: Isonicotinic Acid Vanillylidenehydrazide exhibits anti-mycobacterial activity against Mycobacterium tuberculosis and anti-microbial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans, and Aspergillus niger. Also, it is derived from Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic). Molecular Formula: C14H13N3O3 Molecular Weight: 271.27 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.