Herbicidin A

Size

£544.00

SKU:: 451795
Molecular Weight:: 551.5
Purity:: ≥95%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 55353-31-6
Extra Details:: Herbicidin A is an adenine nucleoside antibiotic originally isolated from S. saganonensis that exhibits herbicidal activity, particularly against dicotyledonous plants.1,2 It prevents rice seed germination (MIC = 6.25 ug/ml) and completely protects young rice plants from X. oryzae-induced leaf blight when applied at 100 ppm.1 In HEK293 cells, herbicidin A inhibits TNF-α-induced NF-κB activity and induces cytotoxicity (IC50s = 1.8 and 2.7 uM, respectively).3 Source: Bacterium/Streptomyces sp. MST-94754 Synonyms: (7R)-1-(6-amino-9H-purin-9-yl)-6,10-anhydro-1,5-dideoxy-2-O-methyl-D-arabino-α-L-ido-7-undeculo-7,3-pyranose-1,4-furanuronic acid, 8-[(2E)-2-(hydroxymethyl)-2-butenoate], methyl ester CAS Number: 55353-31-6 Molecular Formula: C₂₃H₂₉N₅O₁₁ Molecular Weight: 551.5 Solubility and Usage: Herbicidin A is supplied as a solid. A stock solution may be made by dissolving the herbicidin A in the solvent of choice. Herbicidin A is soluble in organic solvents such as ethanol, methanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. Purity: ≥95% Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.