Heptelidic Acid

Size

£362.00

SKU:: 451781
Molecular Weight:: 280.32
Purity:: ≥95% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 57710-57-3
Format:: Supplied as a white solid.
Extra Details:: Antibiotic. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols. Source: Isolated from Trichoderma sp. Synonyms: Koningic acid; Avocettin; FO-4443; BRN 5091359 CAS Number: 57710-57-3 (74310-84-2 deleted) Molecular Weight: 280.3 Molecular Formula: C15H20O5 Solubility: DMSO (10mg/ml), ethanol (1mg/ml), methanol (1mg/ml) or water (1mg/ml). Appearance: Supplied as a white solid. Purity: ≥95% (HPLC) Storage and Stability: May be stored at 4°C for short-term only. Keep cool and dry. Stable for 12 months after receipt when stored at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.