Epothilone D-13C2,15N

Size

£639.00

SKU:: 448345
Molecular Weight:: 494.66
Storage Conditions:: -20°C
Supplier:: United States Biological
Extra Details:: Epothilone D-13C2,15N is the isotopically labelled form of synthetic Epothilone D (E589000), which is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones polyketide natural products. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers. Epothilone D is in phase I of clinical testing in patients with advanced solid tumors. Molecular Formula: C2513C2H4115NO5S Molecular Weight: 494.66 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.