Dorsomorphin Dihydrochloride

Size

£390.00

SKU:: 447668
Molecular Weight:: 472.41
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1219168-18-9
Format:: Supplied as a Yellow Solid
Extra Details:: Dorsomorphin is an AMP-activated kinase (AMPK) inhibitor. Dorsomorphin selectively inhibits the bone morphogenetic protein (BMP) type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation, target gene transcription and osteogenic differentiation. Dorsomorphin has shown to to increase cisplatin-induced apoptosis, which was associated with hyper-induction of the tumor suppressor p53. Molecular Formula: C24H27Cl2N5O Solubility: DMSO, Water Molecular Weight: 472.41 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.