DDAO

Size

£338.00

SKU:: 445830
Molecular Weight:: 308.16
Purity:: ≥98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 118290-05-4
Format:: Solid
Extra Details:: DDAO is a near-infrared (NIR) red fluorescent probe with tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm) and a relatively low pKa (~5)[1]. DDAO can be used to detect the activities of different enzymes, such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin, and esterase. There is a linear relationship between protein phosphatase 2A (PP-2A) concentration and DDAO-induced fluorescence[2]. DDAO can be used to study the phagocytosis of cancer cells by macrophages[3]. DDAO can be used to study the proliferation of B cells[4]. Synonyms: 7-hydroxy-9H-(1,3-dichloro-9,9-dimethylacridin-2-one CAS No: 118290-05-4 Molecular Formula: C₁₅H₁₁Cl₂NO₂ Molecular Weight: 308.16 Appearance: Solid Purity: ≥98% (HPLC) NMR: Conforms to reference Extinction Coefficient: 40000 (cm -1 M -1) Excitation (nm): 648 Emission (nm): 658 Solubility: DMSO: 10mg/ml Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.