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443040

Blonanserin C

Size

£530.00

SKU:
443040
Molecular Weight:
339.45
Purity:
≥95%
Storage Conditions:
-20°C
Supplier:
United States Biological
CAS Number:
132811-84-8
Format:
White to off-white solid
Extra Details:
Blonanserin C is an intermediate in the synthesis of Blonanserin, a 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic. Blonanserin C is an atypical antipsychotic drug that has been shown to be effective in the treatment of schizophrenia. This drug has been studied in healthy Chinese subjects and was found to have a long-term efficacy in the treatment of schizophrenia. Blonanserin C is metabolized by cytochrome P450 enzymes and excreted by the kidneys, with a half-life of approximately 18 hours. The pharmacokinetics of blonanserin C have been investigated using liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. The major metabolites of blonanserin C are N-desmethylblonanserin and 2′,3′-didehydroblonanserin. Synonyms: Blonanserin Metabolite 5; 4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydro-2-(1-piperazinyl)cycloocta[b]pyridine; N1-ethyl-N2-(4-(4-fluorophenyl)-5, 6, 7, 8, 9, 10-hexahydrocycloocta[b]pyridin-2-yl)ethane-1, 2-diamine CAS No: 132811-84-8 Molecular Formula: C21H26FN3 Molecular Weight: 339.45 Appearance: White to off-white solid Purity: ≥95% Melting Point: 148°C Solubility: DCM, Ethyl Acetate Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Ambient