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442677

BI-78D3

Size

£275.00

SKU:
442677
Molecular Weight:
379.37
Storage Conditions:
-20°C
Supplier:
United States Biological
CAS Number:
883065-90-5
Extra Details:
BI-78D3 is an inhibitor of JNK mediated signaling. Molecular docking studies on JNK inhibitors at allosteric JNK-JIP interaction site. JNK inhibition by BI-78D3 covalent binding to JNK at Cys163 or displacement of 2-mercapto-5-nitrothiazole, or addition of BI-78D3 oxidation product. A therapeutic target of the vascular JNK pathway which improves retinal endothelial vasodilator function during early diabetes. Molecular Formula: C13H9N5O5S2 Molecular Weight: 379.37 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Ambient