441904

Atrasentan

Size

£479.00

SKU:: 441904
Molecular Weight:: 510.62
Purity:: ≥99% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 173937-91-2
Format:: White to off-white solid
Extra Details:: Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation. Used in studies related to glomerular disease and diabetic nephropathy. Synonyms: ABT-627; A-147627; (+)-A 127722; (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic Acid, (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid CAS No: 173937-91-2 Molecular Formula: C₂₉H₃₈N₂O₆ Molecular Weight: 510.62 Appearance: White to off-white solid Purity: ≥99% (HPLC) NMR, C NMR, MS: Conforms to reference Melting Point: 121-126ºC Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.