Agmatine Sulfate-15N2, 13C

Size

£607.00

SKU:: 441063
Molecular Weight:: 231.25
Storage Conditions:: -20°C
Supplier:: United States Biological
Extra Details:: General Uses: Neuroprotective, CNS studies, Autism and depression research Description: Agmatine Sulfate-15N2, 13C is a labeled analogue of Agmatine Sulfate, a polyamine derived from L-arginine decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDA-receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3) Molecular Formula: C413CH16N215N2O4S Molecular Weight: 231.25 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.