Acalabrutinib

Size

£433.00

SKU:: 440755
Molecular Weight:: 465.51
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 1420477-60-6
Extra Details:: Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL). Synonyms: 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1- yl]-N-2-pyridinylbenzamide; ACP 196 CAS No: 1420477-60-6 Molecular Formula: C26H23N7O2 Molecular Weight: 465.51 Purity (HPLC): ≥98% Appearance: Light yellow to yellow solid Solubility: DMSO (Slightly), Methanol (Slightly) NMR, CNMR, LC-MS: Conforms to reference Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.