5,6-Dihydrouridine

Size

£307.00

SKU:: 437195
Molecular Weight:: 246.22
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 5627-05-4
Extra Details:: 5,6-Dihydrouridine is an intermediate used in the synthesis of 3,4,5,6-Tetrahydrouridine which is a derivative of Uridine.Tetrahydrouridine (THU) is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA. Synonyms: Dihydro-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Dihydrouridine; 1-β-D-Ribofuranosyl-hydrouracil CAS Number: 5627-05-4 Molecular Formula: C₉H₁₄N₂O₆ Molecular Weight: 246.22 Purity: ≥96% Appearance: White to off-white solid Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis TLC Conditions: SiO2; Dichloromethane: Methanol=8:2 Visualized with UV and AMCS; Single Spot, Rf=0.45 Elemental Analysis: Calculated: %C: 43.90, %H: 5.73, %N: 11.38 Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly) Specific Rotation: As reported Storage and Stability: Store at 4°C under inert atmosphere. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap