3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-N-(3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)propanamide

Size

£479.00

SKU:: 422570
Molecular Weight:: 826.95
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a Off-white Solid
Extra Details:: 3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-N-(3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)propanamide is an intermediate in the synthesis of Namino-{3-[(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)- 1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]-propionyl} Ibrutinib (A619015), which is an impurity of Ibrutinib (I124970), a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor. Molecular Formula: C47H46N12O3 Solubility: Dichloromethane, Methanol Molecular Weight: 826.95 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.