11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one-d2

Size

£288.00

SKU:: 411762
Molecular Weight:: 284.31
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a Yellow Solid
Extra Details:: 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one-d2 is a labelled analogue of 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one (C988365), which is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral. 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one-d2 is also an intermediate in synthesizing Nevirapine-d2 (N391276), an isotope labelled Nevirapine (N391275), which acts as a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral. Molecular Formula: C15H12D2N4O2 Solubility: Chloroform, Methanol Molecular Weight: 284.31 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.