1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone

Size

£422.00

SKU:: 408656
Molecular Weight:: 408.3
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1253056-01-7
Format:: Supplied as a white to off-white solid.
Extra Details:: 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Molecular Formula: C16H14F6N4O2 Solubility: Chloroform (Slightly), Methanol (Slightly) Molecular Weight: 408.3 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.