DUOX2 (Dual Oxidase 2, Large NOX 2, Long NOX 2, NADH/NADPH Thyroid Oxidase p138-tox, NADPH Oxidase/peroxidase DUOX2, NADPH Thyroid Oxidase 2, Thyroid Oxidase 2, p138 Thyroid Oxidase, DUOX2, LNOX2, THOX2)

Size

£394.00

SKU:: 406371
Purity:: Purified by immunoaffinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa1-100 of human DUOX2
Format:: Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol
Extra Details:: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 1:20-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.