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404836

STEAP4 (Metalloreductase STEAP4, STAMP2, Six-transmembrane Epithelial Antigen of Prostate 4, Six Transmembrane Protein of Prostate 2, Tumor Necrosis Factor, alpha-induced Protein 9, TNFAIP9)

Size

£479.00

SKU:
404836
Purity:
Purified by immunoaffinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to aa201-250 from human STEAP4.
Format:
Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Extra Details:
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Immunohistochemistry, Immunofluorescence and ELISA. Other applications not tested. Recommended Dilutions: Immunohistochemistry (paraffin): 1:100-1:300 Immunofluorescence: 1:200-1:1000 ELISA: 1:20,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice