IL-17A (Interleukin-17A)

Size

£850.00

SKU:: 397101
Purity:: Purified by immunoaffinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to bovine IL-17A.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: IL-17A is a 35kD disulfide-linked homodimer consisting of two 153aa chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17, originally thought to have been produced primarily by activated CD4+ T cells, appears to have a range of cellular origins and induces a variety of target cells to secrete inflammatory cytokines, including IL-1 beta, IL-6, TNF alpha, IFN gamma and granulocyte colonystimulating factor, as well as synergizing with other inflammatory cytokines and agonists. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1-10ug/ml Western Blot: 0.1-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.